``Stem cells'' have become a common topic in beauty clinics, beauty salons, cosmetics, etc. Stem cells are cells that have the ability to divide, proliferate, and repair on their own, and because they have the function of replenishing tissues and cells lost in the body, they are used as "regenerative medicine" in addition to treating diseases and injuries. It is also attracting attention from a beauty perspective such as anti-aging.
Stem cell culture fluid, which is often used in cosmetics and other self-care items, is the supernatant fluid produced during the process of culturing stem cells. It is rich in various growth factors such as cytokines secreted by stem cells (nutritional ingredients that increase cell activity, a type of protein), so direct application is expected to treat skin and body problems. That's what I'm doing.
Benefits of human origin
Stem cells are broadly divided into three types: human stem cells, plant stem cells, and animal stem cells. Human stem cells derived from humans are often used in medical and beauty fields, and there is a reason for this.
It is said that our bodies are made up of 37 trillion cells, and each cell has a key hole (receptor) on its surface that has a different shape depending on the cell's properties. It cannot be received unless it is a substance that has a key (ligand) that binds to it. In other words, in order for cells to activate, a substance that has a key that fits perfectly is essential.
Since plant cells have different mechanisms, the factors contained in the culture medium are not the key. In addition, animal cells have different protein shapes than humans, so the structure of the key changes, making it difficult for them to receive it. It is believed that the nutritional ingredients (factors) made from human cells make it easier to penetrate and deliver the ingredients.
Cytokine, a key component of cell activation
The "cytokines" abundantly contained in human stem cell culture medium have different properties. For example, EGF (epidermal growth factor), which is used in cosmetics, binds easily to cells in the epidermis and has the effect of regulating skin turnover, while FGF (fibroblast growth factor) promotes the proliferation of dermal fibroblasts and collagen fibers. It has the function of creating
In this way, just one type of cytokine has an effect, but when a variety of cytokines with different properties and keys come together, various cells can receive the components and exert a synergistic effect. It is expected that.
Human stem cell culture fluid is attracting attention in the medical and beauty worlds because it has the potential to directly affect the cells that form our origins.